Debian :: Delete A File On Every Startup?

I would like to delete some files stored in the personal directory, say .adobe, .macromedia, .xsession-errors, on every start-up or shutting down. I can do it with cron but I would like to learn different (simpler) options. The thing is, I haven't been able to input the proper terms in a search engine. Note that these files must exist in their default location during the session. This is, I don't want to make them links to /dev/null or move them to /tmp.